ML213 is a selective activator of Kv7.2 (KCNQ2) and Kv7.4 (KCNQ4) channels, enhances Kv7.2 and Kv7.4 channels with EC50s of 230 and 510 nM, respectively.

TREM2 agonist-2 (I-192) is an orally active and potent agonist of myeloid triggered receptor 2 (TREM2) for neurodegenerative disease research.

Adrenocorticotropic Hormone (ACTH) (4-10) is an agonist of potent melanocortin(MC4R) receptor.In humans, Adrenocorticotropic Hormone (ACTH) (4-10)?enters the cerebral fluid compartment after intranasal application and leads to a?decrease in total body fat after 6 weeks of continuous treatment.