Litorin( ——— )

Catalog No. M41885 CAS No. 55749-97-8

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Product Name

Litorin
Note

Research use only, not for human use.
Brief Description

Litorin, an amphibian bombesin peptide derivative, is an bombesin receptor agonist. Litorin stimulates the contraction of smooth muscle, stimulates gastrin, gastric acid, and pancreatic secretion, and suppresses the nutriment in vivo.
Description

Litorin, an amphibian bombesin peptide derivative, is found to suppress the nutriment, to stimulate the contraction of smooth muscle, to stimulate gastrin, gastric acid, and pancreatic secretion.
In Vitro

99mTc-Litorin is developed for non-invasive imaging of tumors with overexpressed gastrin-releasing peptide receptors (GRP-R).[D-Phe1,Leu8,9]Litorin inhibits binding of 125I-[Tyr4] BN to murine Swiss 3T3 cells with a Ki of 5.1 nM.Litorin stimulates 3H-Thymidine incorporation in murine Swiss 3T3 cells with an EC50 of 2.3 nM.
In Vivo

Litorin stimulates the contraction of smooth muscle, stimulates gastrin, gastric acid, and pancreatic secretion, and suppresses the nutriment in in vivo experiments.
Synonyms

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Pathway

Others
Target

Other Targets
Recptor

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Research Area

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Indication

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CAS Number

55749-97-8
Formula Weight

1085.24
Molecular Formula

C51H68N14O11S
Purity

>98% (HPLC)
Solubility

DMSO : 100 mg/mL (92.15 mM; ultraphonic; ) H2O : 2 mg/mL (1.84 mM; ultraphonic (<60 ℃)； (HCL ，pH=3) )
SMILES

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Chemical Name

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1. Kam Leung. 99mTc-pGlu-Gln-Trp-Ala-Val-Gly-His-Phe-Met-NH2. Molecular Imaging and Contrast Agent Database (MICAD). 2007 Oct 1.?

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