Isopicropodophyllone, a natural compound that can be isolated from leaves of Podophyllum hexandrum, possesses antifungal activity.

C188-9 is a Stat3 inhibitor with an IC50 of 4-7 μM.

Endogenous agonist at orexin receptors (Ki values are 20 and 38 nM for OX1 and OX2 receptors respectively). Stimulates feeding following central administration and may be involved in the control of sleep-wake cycle and other hypothalamic functions.