Meclocycline (INN) is a tetracycline antibiotic. It is used topically (i.e. for skin infections) as it is totally insoluble in water and may cause liver and kidney damage if given systemically.

Nootkatone can prevent obesity and improve physical performance through AMPK activation in skeletal muscle and liver.

Neuromedin U,a 23-amino acid brain-gut peptide, regulates several important physiological functions through its cognate receptor NMUR2 in the central nervous system, including energy balance, stress response, and nociception.