The Staphylococcus aureus transpeptidase Sortase A (SrtA) anchors virulence and colonization-associated surface proteins to the cell wall. SrtA selectively recognizes a C-terminal LPXTG motif. SrtA readily reacts with its native substrate Abz-LPETG-Dap(DNP)-NH2, cleaving it and catalyzing the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges.

6-Methylcoumarin (6MC) is a semisynthetic coumarin with important?in vitro?and?in vivo?anti-inflammatory activity.?

Demethoxycurcumin is found in Curcuma zedoaria and Etlingera elatior. It has a role as a metabolite an antineoplastic agent and an anti-inflammatory agent.