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β-Endorphin (6-31), human
CAS No. 77761-27-4
β-Endorphin (6-31), human( ——— )
Catalog No. M41088 CAS No. 77761-27-4
β-Endorphin, an endogenous opioid neuropeptide, is an opioid receptor agonist. β-Endorphin binds preferentially to μ-opioid receptors and is produced in certain neurons of the central and peripheral nervous system and is one of three endorphins produced in humans. β-Endorphin can be used to reduce stress and maintain homeostasis in the body and is involved in neurological pain perception regulation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
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Biological Information
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Product Nameβ-Endorphin (6-31), human
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NoteResearch use only, not for human use.
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Brief Descriptionβ-Endorphin, an endogenous opioid neuropeptide, is an opioid receptor agonist. β-Endorphin binds preferentially to μ-opioid receptors and is produced in certain neurons of the central and peripheral nervous system and is one of three endorphins produced in humans. β-Endorphin can be used to reduce stress and maintain homeostasis in the body and is involved in neurological pain perception regulation.
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Descriptionβ-Endorphin, an endogenous opioid neuropeptide, is an opioid receptor agonist. β-Endorphin binds preferentially to μ-opioid receptors and is produced in certain neurons of the central and peripheral nervous system and is one of three endorphins produced in humans. β-Endorphin can be used to reduce stress and maintain homeostasis in the body and is involved in neurological pain perception regulation.
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In Vitro———
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In Vivoβ-Endorphin (0.03 to 1.00?μg/kg, i.p., once) impairs retention of a one-trial inhibitory avoidance task in a dose-dependent manner in male Swiss mice immediately post-training. Also, it works in the process of memory consolidation.Animal Model:Adult male Swiss mice (22-25 g)Dosage:0.03, 0.10, 0.30 or 1.00 μg/kg Administration:i.p., once Result:Significantly impaired retention at the doses of 0.03 and 0.10?μg/kg while not significantly affect retention as compared with the control group at the two higher doses of 0.30 and 1.00?μg/kg , but tended to increase retention as compared with the dose of 0.10?μg/kg.Increased latencies to step-through at the two higher doses of 0.30 and 1.00?μg/kg but no effect at lower doses.
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Synonyms———
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PathwayOthers
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TargetOther Targets
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Recptor———
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Research Area———
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Indication———
Chemical Information
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CAS Number77761-27-4
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Formula Weight2909.38
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Molecular FormulaC131H218N34O40
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Purity>98% (HPLC)
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Solubility———
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SMILES———
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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