α-Conotoxin IMI( ——— )

Catalog No. M41030 CAS No. 156467-85-5

α-Conotoxin Im-I is a selective α7/α9 nAChR antagonist, blocking α7 nicotinic receptors with the highest apparent affinity, while having an 8-fold lower affinity for homomeric α9 nicotinic receptors. α-Conotoxin Im-I is toxic and induces seizures in rodents. α-Conotoxin Im-I is a tool for studying neuronal nAChR.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

α-Conotoxin IMI
Note

Research use only, not for human use.
Brief Description

α-Conotoxin Im-I is a selective α7/α9 nAChR antagonist, blocking α7 nicotinic receptors with the highest apparent affinity, while having an 8-fold lower affinity for homomeric α9 nicotinic receptors. α-Conotoxin Im-I is toxic and induces seizures in rodents. α-Conotoxin Im-I is a tool for studying neuronal nAChR.
Description

alpha-Conotoxin imi is a nicotinic acetylcholine receptor ligand.
In Vitro

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In Vivo

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Synonyms

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Pathway

Others
Target

Other Targets
Recptor

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Research Area

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Indication

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Chemical Information

CAS Number

156467-85-5
Formula Weight

1347.58
Molecular Formula

C52H74N20O15S4
Purity

>98% (HPLC)
Solubility

DMSO : 100 mg/mL (73.99 mM; ultraphonic; )
SMILES

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Chemical Name

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Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Johnson DS, et al. alpha-Conotoxin ImI exhibits subtype-specific nicotinic acetylcholine receptor blockade: preferential inhibition of homomeric alpha 7 and alpha 9 receptors. ?

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