Tesnatilimab is a potent humanized IgG4 monoclonal antibody that binds to the immune-activating receptor NKG2D.

Mitazalimab (ADC-1013; JNJ-64457107) is an FcγR-dependent CD40 agonist that targets tumors by activating antigen-presenting cells like dendritic cells (DC), initiating tumor-reactive T cells, promoting tumor-specific T cell infiltration and destruction of tumors, and remodeling the tumor-infiltrating myeloid microenvironment .

NADP disodium salt is a nicotinamide adenine dinucleotide. NADP disodium salt is a key redox cofactor for electron transfer in the metabolism, serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH).