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(D-Pro4,D-Trp7·9,Nle11)-Substance P (4-11)

CAS No. 89430-34-2

(D-Pro4,D-Trp7·9,Nle11)-Substance P (4-11)( ——— )

Catalog No. M40453 CAS No. 89430-34-2

[D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) is a potent neurokinin NK1 antagonist. [D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) inhibits the effects of gold-protein-substance P (GPSP) and substance P (SP).

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    (D-Pro4,D-Trp7·9,Nle11)-Substance P (4-11)
  • Note
    Research use only, not for human use.
  • Brief Description
    [D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) is a potent neurokinin NK1 antagonist. [D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) inhibits the effects of gold-protein-substance P (GPSP) and substance P (SP).
  • Description
    [D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) is a potent neurokinin NK1 antagonist. [D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) inhibits the effects of gold-protein-substance P (GPSP) and substance P (SP).
  • In Vitro
    [D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) (100 nM) dose not exert a direct relaxant or contractile effect, but significantly reduces the vasodilatation induced by SP and GPSP.
  • In Vivo
    ———
  • Synonyms
    ———
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ———
  • Research Area
    ———
  • Indication
    ———

Chemical Information

  • CAS Number
    89430-34-2
  • Formula Weight
    1116.34
  • Molecular Formula
    C58H77N13O10
  • Purity
    >98% (HPLC)
  • Solubility
    ———
  • SMILES
    ———
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Cathieni M M, et al. Pharmacological Evidence that Gold-Protein-Substance P Complex Activates Neurokinin NK1 ReceptorsJ. Cellular Physiology & Biochemistry, 1995, 5(2):85-95.
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