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(D-Pro4,D-Trp7·9,Nle11)-Substance P (4-11)
CAS No. 89430-34-2
(D-Pro4,D-Trp7·9,Nle11)-Substance P (4-11)( ——— )
Catalog No. M40453 CAS No. 89430-34-2
[D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) is a potent neurokinin NK1 antagonist. [D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) inhibits the effects of gold-protein-substance P (GPSP) and substance P (SP).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product Name(D-Pro4,D-Trp7·9,Nle11)-Substance P (4-11)
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NoteResearch use only, not for human use.
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Brief Description[D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) is a potent neurokinin NK1 antagonist. [D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) inhibits the effects of gold-protein-substance P (GPSP) and substance P (SP).
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Description[D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) is a potent neurokinin NK1 antagonist. [D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) inhibits the effects of gold-protein-substance P (GPSP) and substance P (SP).
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In Vitro[D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) (100 nM) dose not exert a direct relaxant or contractile effect, but significantly reduces the vasodilatation induced by SP and GPSP.
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In Vivo———
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Synonyms———
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PathwayOthers
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TargetOther Targets
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Recptor———
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Research Area———
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Indication———
Chemical Information
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CAS Number89430-34-2
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Formula Weight1116.34
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Molecular FormulaC58H77N13O10
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Purity>98% (HPLC)
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Solubility———
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SMILES———
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Cathieni M M, et al. Pharmacological Evidence that Gold-Protein-Substance P Complex Activates Neurokinin NK1 ReceptorsJ. Cellular Physiology & Biochemistry, 1995, 5(2):85-95.
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