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Substance P (5-11)

CAS No. 51165-09-4

Substance P (5-11)( ——— )

Catalog No. M40437 CAS No. 51165-09-4

Substance P (5-11), the C-terminal heptapeptide of Substance P (Substance P ), is a neuropeptide. Substance P (5-11) binds to NK-1 tachykinin receptor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Substance P (5-11)
  • Note
    Research use only, not for human use.
  • Brief Description
    Substance P (5-11), the C-terminal heptapeptide of Substance P (Substance P ), is a neuropeptide. Substance P (5-11) binds to NK-1 tachykinin receptor.
  • Description
    Substance P (5-11), the C-terminal heptapeptide of Substance P (Substance P )), is a neuropeptide. Substance P (5-11) binds to NK-1 tachykinin receptor.
  • In Vitro
    When a fraction from rabbit brain enriched in glial cells was incubated with [3H]Substance P (5-11), an uptake of [3H]Substance P (5-11) is observed. When Substance P is released from nerve terminals, it is hydrolysed into Substance P (5-11), which is in turn accumulated into glial cells as well as nerve terminals and that this high affinity uptake mechanism may play an important role in terminating the synaptic action of Substance P.
  • In Vivo
    ———
  • Synonyms
    ———
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ———
  • Research Area
    ———
  • Indication
    ———

Chemical Information

  • CAS Number
    51165-09-4
  • Formula Weight
    869.06
  • Molecular Formula
    C41H60N10O9S
  • Purity
    >98% (HPLC)
  • Solubility
    ———
  • SMILES
    ———
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. A Inoue, et al. Active uptake system for substance P carboxy-terminal heptapeptide (5-11) into a fraction from rabbit enriched in glial cells. Jpn J Pharmacol. 1984 Oct;36(2):137-45.?
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