Cart
sales@molnova.com
Substance P (1-4)
CAS No. 57468-16-3
Substance P (1-4)( ——— )
Catalog No. M40433 CAS No. 57468-16-3
Substance P(1-4) is a potent neurokinin receptors (NK-R) antagonist. Substance P(1-4) has regulation of normal hematopoiesis and inhibits endogenous erythroid colony (EEC) formation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | Get Quote | Get Quote |
|
| 50MG | Get Quote | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameSubstance P (1-4)
-
NoteResearch use only, not for human use.
-
Brief DescriptionSubstance P(1-4) is a potent neurokinin receptors (NK-R) antagonist. Substance P(1-4) has regulation of normal hematopoiesis and inhibits endogenous erythroid colony (EEC) formation.
-
DescriptionSubstance P(1-4) is a potent neurokinin receptors (NK-R) antagonist. Substance P(1-4) has regulation of normal hematopoiesis and inhibits endogenous erythroid colony (EEC) formation.
-
In VitroSubstance P(1-4) (0.1 nM-1 μM) inhibits endogenous erythroid colony (EEC) formation in PV bone marrow cultures.Substance P(1-4) (0.1 nM-1 μM; CD36+/GpA- cells) decreases of erythroid colony numbers of 47% and inhibits proliferation of PV CD36+/GpA- cells of 30 %.Cell Viability Assay Cell Line:PV CD36+/GpA- cells Concentration:0.1 nM-1 μM Incubation Time:2 days Result:Inhibited proliferation of PV CD36+/GpA- cells of 30 %.Apoptosis Analysis Cell Line:PV CD36+/GpA- cells Concentration:10 nM Incubation Time:2 days Result:Increased the percentage of cell death of 27.3%.
-
In Vivo———
-
Synonyms———
-
PathwayOthers
-
TargetOther Targets
-
Recptor———
-
Research Area———
-
Indication———
Chemical Information
-
CAS Number57468-16-3
-
Formula Weight496.6
-
Molecular FormulaC22H40N8O5
-
Purity>98% (HPLC)
-
Solubility———
-
SMILES———
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Le Gall C, et, al. Inhibitory effect of the substance P and its derivative on erythropoietin-independent growth of erythroid progenitors in polycythemia vera. Leuk Res. 2008 May;32(5):743-54.?
molnova catalog
related products
-
Cholestyramine
Cholestyramine, a bile acid-binding resin, inhibits intestinal bile acid absorption which results in the increasing bile acid synthesis from cholesterol.
-
C. difficile Toxin B...
C. difficile Toxin B (248 - 262)
-
mono-Methyl glutarat...
Monomethyl glutaric acid is a metabolite of dibasic esters(DBEs) by nasal respiratory and olfactory mucosae in vitro demonstrated that hydrolysis of DBEs yields mainly the monomethyl esters (monomethyl adipate monomethyl. glutarate and monomethyl succinate).
