Substance P (1-4)

CAS No. 57468-16-3

Substance P (1-4)( ——— )

Catalog No. M40433 CAS No. 57468-16-3

Substance P(1-4) is a potent neurokinin receptors (NK-R) antagonist. Substance P(1-4) has regulation of normal hematopoiesis and inhibits endogenous erythroid colony (EEC) formation.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
25MG Get Quote Get Quote
50MG Get Quote Get Quote
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Substance P (1-4)
  • Note
    Research use only, not for human use.
  • Brief Description
    Substance P(1-4) is a potent neurokinin receptors (NK-R) antagonist. Substance P(1-4) has regulation of normal hematopoiesis and inhibits endogenous erythroid colony (EEC) formation.
  • Description
    Substance P(1-4) is a potent neurokinin receptors (NK-R) antagonist. Substance P(1-4) has regulation of normal hematopoiesis and inhibits endogenous erythroid colony (EEC) formation.
  • In Vitro
    Substance P(1-4) (0.1 nM-1 μM) inhibits endogenous erythroid colony (EEC) formation in PV bone marrow cultures.Substance P(1-4) (0.1 nM-1 μM; CD36+/GpA- cells) decreases of erythroid colony numbers of 47% and inhibits proliferation of PV CD36+/GpA- cells of 30 %.Cell Viability Assay Cell Line:PV CD36+/GpA- cells Concentration:0.1 nM-1 μM Incubation Time:2 days Result:Inhibited proliferation of PV CD36+/GpA- cells of 30 %.Apoptosis Analysis Cell Line:PV CD36+/GpA- cells Concentration:10 nM Incubation Time:2 days Result:Increased the percentage of cell death of 27.3%.
  • In Vivo
    ———
  • Synonyms
    ———
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ———
  • Research Area
    ———
  • Indication
    ———

Chemical Information

  • CAS Number
    57468-16-3
  • Formula Weight
    496.6
  • Molecular Formula
    C22H40N8O5
  • Purity
    >98% (HPLC)
  • Solubility
    ———
  • SMILES
    ———
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Le Gall C, et, al. Inhibitory effect of the substance P and its derivative on erythropoietin-independent growth of erythroid progenitors in polycythemia vera. Leuk Res. 2008 May;32(5):743-54.?
molnova catalog
related products
  • Blebbistatin (b)

    (+)-Blebbistatin is the inactive enantiomer of (–)-Blebbistatin. (–)-Blebbistatin is a selective myosin II ATPase inhibitor.

  • N-(2-hydroxyethyl)-N...

    N-(2-hydroxyethyl)-Naphthalimide is a fluorescent probe for nucleic acid detection whose fluorescence can be burst.

  • 4-O-beta-Glucopyrano...

    4-O-beta-Glucopyranosyl-cis-coumaric acid is a natural product.