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Somatostatin-28 a

CAS No. 73032-94-7

Somatostatin-28 a( ——— )

Catalog No. M40423 CAS No. 73032-94-7

Somatostatin-28 (sheep, human rat mouse) is a biologically active polypeptide, synthesised in the proximal intestinal epithelial cells. Somatostatin-28 (sheep, human rat mouse) suppresses glucose-stimulated insulin secretion without affecting circulating basal insulin concentration. Somatostatin-28 (sheep, human rat mouse) also targets to somatostatin receptor subtype 5 (SSTR5) to regulate GLP-1 secretion.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Somatostatin-28 a
  • Note
    Research use only, not for human use.
  • Brief Description
    Somatostatin-28 (sheep, human rat mouse) is a biologically active polypeptide, synthesised in the proximal intestinal epithelial cells. Somatostatin-28 (sheep, human rat mouse) suppresses glucose-stimulated insulin secretion without affecting circulating basal insulin concentration. Somatostatin-28 (sheep, human rat mouse) also targets to somatostatin receptor subtype 5 (SSTR5) to regulate GLP-1 secretion.
  • Description
    Somatostatin-28 (sheep, human rat mouse) is a biologically active polypeptide, synthesised in the proximal intestinal epithelial cells.
  • In Vitro
    ———
  • In Vivo
    Animal Model:Finn-Dorset Horn cross bred sheep (2-5 years old, 70-75 kg) Dosage:1.1 pmol/kg/min for 15 min, with or without 25 μg/kg/min glucose;Administration:Intravenous injection via a jugular catheter;Result:Significantly inhibited insulin secretion, resulted serum concentrations decreasing from about 200 to 150 pmol/L.
  • Synonyms
    ———
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    SSTR5
  • Research Area
    ———
  • Indication
    ———

Chemical Information

  • CAS Number
    73032-94-7
  • Formula Weight
    3148.56
  • Molecular Formula
    C137H207N41O39S3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 100 mg/mL (31.76 mM; ultraphonic; )
  • SMILES
    ———
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Martin PA, et al. Effects of somatostatin-28 on circulating concentrations of insulin and gut hormones in sheep. J Endocrinol. 1996 Oct;151(1):107-12. ?
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