(Nle4)-α-MSH

Research use only, not for human use.

(Nle4)-α-MSH is a synthetic analogue of α-MSH, a melanocyte-stimulating hormone. (Nle4)-α-MSH reversibly darkens frog skins and also exhibits prolonged activity after heat-alkali treatment.

(Nle4)-α-MSH is a synthetic analogue of α-MSH, a melanocyte-stimulating hormone. (Nle4)-α-MSH reversibly darkens frog skins and also exhibits prolonged activity after heat-alkali treatment.

(Nle4)-α-MSH shows a better bioactivity than α-MSH in frog skin bioassay, activation of mouse melanoma adenylate cyclase, and stimulation of mouse melanoma cell tyrosinase activity.(Nle4)-α-MSH (0.1 nM; 0.5, 4, 8 h) stimulates tyrosinase activity in melanoma cells .(Nle4)-α-MSH (0.1 nM; 1-4 h) increases biological activity of melanotropins, indicatingdarkening response of frog skins.(Nle4)-α-MSH (0.1 μg) also activates mouse melanoma adenylate cyclase.

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Others

Other Targets

tyrosinase; melanoma adenylate cyclase

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64887-70-3

1646.85

C78H111N21O19

>98% (HPLC)

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(-20℃)

With Ice Pack

≥ 2 years