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GRF (bovine)|GRF (1-44) (BOVINE)

CAS No. 88894-91-1

GRF (bovine)|GRF (1-44) (BOVINE)( ——— )

Catalog No. M40236 CAS No. 88894-91-1

GHRF, bovine (bGRF(1-44)-NH2) is the bovine growth hormone (GH)-releasing factor (GHRF). GHRF, bovineincreases the release of bovine GH, and shows a synergistic effect with Hydrocortisone.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    GRF (bovine)|GRF (1-44) (BOVINE)
  • Note
    Research use only, not for human use.
  • Brief Description
    GHRF, bovine (bGRF(1-44)-NH2) is the bovine growth hormone (GH)-releasing factor (GHRF). GHRF, bovineincreases the release of bovine GH, and shows a synergistic effect with Hydrocortisone.
  • Description
    GHRF, bovine (bGRF(1-44)-NH2) is the bovine growth hormone (GH)-releasing factor (GHRF). GHRF, bovineincreases the release of bovine GH, and shows a synergistic effect with Hydrocortisone.
  • In Vitro
    GHRF, bovine (0.001 nM-100 nM; 6 h) increases growth hormone (GH) release from bovine anterior pituitary cells, with maximum release of 262% above control at 100 nM. GHRF, bovine (0.0001 nM-100 nM; 24 h) linearly increases GH secretion and is enhanced by Hydrocortisone (Cortisol, 10 ng/mL) in anterior pituitary cells cultured in media containing fetal calf serum (FCS).
  • In Vivo
    GHRF, bovine (12 mg/d; i.v.drip; from 118 to 181 d postpartum) has no influence on the mRNA abundance of the liver-type glucose transporter in the liver or kidney of postpartum bovine.GHRF, bovine (12 mg/d; i.v.drip; from 118 to 181 d postpartum) also doesn’t alter the mRNA abundance of the erythrocyte-type or the intestinal-type glucose transporter in the kidney of postpartum bovine, but results individual differences in the mRNA abundance of the intestinal-type glucose transporter in liver.
  • Synonyms
    ———
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ———
  • Research Area
    ———
  • Indication
    ———

Chemical Information

  • CAS Number
    88894-91-1
  • Formula Weight
    5104.72
  • Molecular Formula
    C220H366N72O66S
  • Purity
    >98% (HPLC)
  • Solubility
    ———
  • SMILES
    ———
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Padmanabhan V, et al. Modulation of growth hormone-releasing factor-induced release of growth hormone from bovine pituitary cells. Domest Anim Endocrinol. 1987 Oct;4(4):243-52.?
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