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(D-Arg2,Lys4)-Dermorphin (1-4) amide
CAS No. 118476-85-0
(D-Arg2,Lys4)-Dermorphin (1-4) amide( ——— )
Catalog No. M40130 CAS No. 118476-85-0
DALDA is a potent and highly selective μ-opioid receptor agonist with a Ki of 1.69 nM. DALDA shows antinociceptive and respiratory effects.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 10MG | 314 | Get Quote |
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Biological Information
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Product Name(D-Arg2,Lys4)-Dermorphin (1-4) amide
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NoteResearch use only, not for human use.
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Brief DescriptionDALDA is a potent and highly selective μ-opioid receptor agonist with a Ki of 1.69 nM. DALDA shows antinociceptive and respiratory effects.
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DescriptionDALDA is a potent and highly selective μ-opioid receptor agonist with a Ki of 1.69 nM. DALDA shows antinociceptive and respiratory effects.
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In Vitro———
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In VivoAnimal Model:Male Sprague-Dawley rats (300–350 g)Dosage:0.24, 0.7 and 7 nmol/rat Administration:Intrathecal injection, once Result:Showed antinociceptive effects with an ED50 of 237 pmol/rat in the rat tail-flick test. Inhibited the uptake of NE in spinal cord synaptosomes in a dose-dependent manner. Had no effect on 5-HT uptake. Produced depression in minute ventilation.Animal Model:Male Long-Evans rats, weighing 200-225 g Dosage:0, 0.1 and 1.0 μg/side, 0.5 μL Administration: Lateral cerebral ventricle injection, once Result:Elicited a significant biphasic effect with an initial suppression, an intermediate marked inhibition, followed by significant activation for horizontal movement time, rearing time, and stereotypy time.
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Synonyms———
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PathwayOthers
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TargetOther Targets
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Recptorμ Opioid Receptor/MOR: 1.69 nM (Ki), κ Opioid Receptor/KOR: 4230 nM (Ki), δ Opioid Receptor/DOR: 19200 nM (Ki)
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Research Area———
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Indication———
Chemical Information
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CAS Number118476-85-0
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Formula Weight611.75
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Molecular FormulaC30H45N9O5
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Purity>98% (HPLC)
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Solubility———
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SMILES———
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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