IL-1β (163-171) (human)( ——— )

Catalog No. M40106 CAS No. 106021-96-9

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Product Name

IL-1β (163-171) (human)
Note

Research use only, not for human use.
Brief Description

β-Interleukin I (163-171), human, an immunostimulatory fragment of human IL-1β peptide, is a T cell activator. β-Interleukin I (163-171), human is not an IL-1R-binding domain of IL-1β. β-Interleukin I (163-171), human is a potent adjuvant that enhances the immune response in a variety of exptl. situations.
Description

β-Interleukin I (163-171), human, an immunostimulatory fragment of human IL-1β peptide, is a T cell activator.
In Vitro

β-Interleukin I (163-171), human (12.5-400 μg/mL, 72 h) stimulates mouse thymocyte proliferation.
In Vivo

β-Interleukin I (163-171), human (50 μg, daily, a poorly immunogenic fibrosarcoma (CE-2) of BALB/c mice model) induces a consistent but limited inhibition of tumor growth.β-Interleukin I (163-171), human (1 μmole/kg, i.v.) together with the T-dependent antigen SRBC increases the primary immune response against the antigen.
Synonyms

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Pathway

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Target

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Recptor

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Research Area

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Indication

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1. Nencioni L, et al. In vivo immunostimulating activity of the 163-171 peptide of human IL-1 beta. J Immunol. 1987 Aug 1;139(3):800-4. ?

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