Antide

Research use only, not for human use.

Antide (D-21074) is a potent LHRH antagonist. Antide also can be used for the research of prostatic cancer.

Antide (D-21074) is a potent LHRH antagonist. Antide also can be used for the research of prostatic cancer.

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Animal Model:Cynomolgus monkey and rat Dosage:1, 3, 6, 10 and 15 mg/kg Administration:Subcutaneous, once or on 5 consecutive days Result:Had a dose-dependent inhibitory effect on serum concentration of LH (only rat) and testosterone and on the weights of the testes, prostates and seminal vesicles.Achieved long-lasting castration-like effects at concentrations between 6 (less than or equal to 8 weeks) and 15 mg/kg (greater than 8 weeks) in the rat. Induced a prolonged inhibitory effect only at 15 mg/kg and the duration was only 2-3 weeks in the cynomolgus monkey.

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Others

Other Targets

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112568-12-4

1591.29

C82H108ClN17O14

>98% (HPLC)

H2O : 10 mg/mL (6.28 mM; ultraphonic)

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(-20℃)

With Ice Pack

≥ 2 years