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Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated)

CAS No. 131791-98-5

Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated)( ——— )

Catalog No. M39961 CAS No. 131791-98-5

Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) is a hirugen-like peptide, and has high affnity for thrombin than Hirugen, with a KD < 100 nM. Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) is an antithrombotic agent. Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) inhibits the thrombin-induced fibrin clot formation with an IC50 value of 0.087 μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated)
  • Note
    Research use only, not for human use.
  • Brief Description
    Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) is a hirugen-like peptide, and has high affnity for thrombin than Hirugen, with a KD < 100 nM. Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) is an antithrombotic agent. Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) inhibits the thrombin-induced fibrin clot formation with an IC50 value of 0.087 μM.
  • Description
    Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) is a hirugen-like peptide, and has high affnity for thrombin than Hirugen, with a KD < 100 nM.
  • In Vitro
    ———
  • In Vivo
    ———
  • Synonyms
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  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ———
  • Research Area
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  • Indication
    ———

Chemical Information

  • CAS Number
    131791-98-5
  • Formula Weight
    1445.5
  • Molecular Formula
    C64H88N10O26S
  • Purity
    >98% (HPLC)
  • Solubility
    ———
  • SMILES
    ———
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Dekker RJ, et al. The variable region-1 from tissue-type plasminogen activator confers specificity for plasminogen activator inhibitor-1 to thrombin by facilitating catalysis: release of a kinetic block by a heterologous protein surface loop. J Mol Biol. 1999 Oct 29;293(3):613-27.?
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