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H-Gly-Pro-Arg-OH
CAS No. 47295-77-2
H-Gly-Pro-Arg-OH( ——— )
Catalog No. M39927 CAS No. 47295-77-2
GPR is a three amino acid peptide. GPR can rescue cultured rat hippocampal neurons from Aβ-induced neuronal death by inhibiting caspase-3/p53 dependent apoptosis. GPR can be used for the research of Alzheimer's disease (AD).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameH-Gly-Pro-Arg-OH
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NoteResearch use only, not for human use.
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Brief DescriptionGPR is a three amino acid peptide. GPR can rescue cultured rat hippocampal neurons from Aβ-induced neuronal death by inhibiting caspase-3/p53 dependent apoptosis. GPR can be used for the research of Alzheimer's disease (AD).
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DescriptionGPR is a three amino acid peptide. GPR can rescue cultured rat hippocampal neurons from Aβ-induced neuronal death by inhibiting caspase-3/p53 dependent apoptosis. GPR can be used for the research of Alzheimer's disease (AD).
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In VitroGPR (1-100 μM; 24 h, 48 h) prevented Aβ-mediated increase in lactate dehydrogenase (LDH) release. GPR (50 μM; 24 h, 48 h) prevents Ah-mediated inhibition of neuronal MTT reduction.GPR (50 μM; 3 days) prevents Aβ-mediated increase in p53-positive cells. Apoptosis Analysis Cell Line:p53-positive cells Concentration:50 μM Incubation Time:3 days Result:Inhibited Ah-induced increase in numbers of p53-positive neurons.
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In Vivo———
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Synonyms———
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PathwayOthers
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TargetOther Targets
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Recptor———
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Research Area———
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Indication———
Chemical Information
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CAS Number47295-77-2
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Formula Weight328.37
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Molecular FormulaC13H24N6O4
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Purity>98% (HPLC)
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Solubility———
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SMILES———
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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