H-Gly-Pro-Arg-OH( ——— )

Catalog No. M39927 CAS No. 47295-77-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Get Quotation Bulk Inquiry Add to Cart

Product Name

H-Gly-Pro-Arg-OH
Note

Research use only, not for human use.
Brief Description

GPR is a three amino acid peptide. GPR can rescue cultured rat hippocampal neurons from Aβ-induced neuronal death by inhibiting caspase-3/p53 dependent apoptosis. GPR can be used for the research of Alzheimer's disease (AD).
Description

GPR is a three amino acid peptide. GPR can rescue cultured rat hippocampal neurons from Aβ-induced neuronal death by inhibiting caspase-3/p53 dependent apoptosis. GPR can be used for the research of Alzheimer's disease (AD).
In Vitro

GPR (1-100 μM; 24 h, 48 h) prevented Aβ-mediated increase in lactate dehydrogenase (LDH) release. GPR (50 μM; 24 h, 48 h) prevents Ah-mediated inhibition of neuronal MTT reduction.GPR (50 μM; 3 days) prevents Aβ-mediated increase in p53-positive cells. Apoptosis Analysis Cell Line:p53-positive cells Concentration:50 μM Incubation Time:3 days Result:Inhibited Ah-induced increase in numbers of p53-positive neurons.
In Vivo

———
Synonyms

———
Pathway

Others
Target

Other Targets
Recptor

———
Research Area

———
Indication

———

Calculator

molnova catalog