Apelin-12 (human, bovine, mouse, rat)( ——— )

Catalog No. M39852 CAS No. 229961-08-4

Apelin-12 is one of the most potent C-terminal fragments of the polypeptide that possesses a high affinity to orphan receptor APJ receptor. Apelin-12 is involved in the regulation of body fluid homeostasis and in the central control of feeding. Apelin-12 blocks HIV-1 entry through APJ receptor. Apelin-12 exerts neuroprotective effect.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	457	In Stock
10MG	743	In Stock
25MG	Get Quote	In Stock
50MG	Get Quote	In Stock
100MG	Get Quote	In Stock

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

Apelin-12 (human, bovine, mouse, rat)
Note

Research use only, not for human use.
Brief Description

Apelin-12 is one of the most potent C-terminal fragments of the polypeptide that possesses a high affinity to orphan receptor APJ receptor. Apelin-12 is involved in the regulation of body fluid homeostasis and in the central control of feeding. Apelin-12 blocks HIV-1 entry through APJ receptor. Apelin-12 exerts neuroprotective effect.
Description

Apelin-12 is one of the most potent C-terminal fragments of the polypeptide that possesses a high affinity to orphan receptor APJ receptor.
In Vitro

Apelin-12 (A12) exerts neuroprotective effect against ischemia-reperfusion injury by inhibiting JNK and p38 MAPK signaling pathway in mouse.Administration of exogenous A12 reduces arterial blood pressure in anesthetized rats due to activation of endothelial nitric oxide synthase and exerts a positive inotropic action in failing myocardium of rodents.Apelin-12 stimulates acid secretion through an increase of histamine release in rat stomachs.
In Vivo

———
Synonyms

———
Pathway

Others
Target

Other Targets
Recptor

HIV-1
Research Area

———
Indication

———

Chemical Information

CAS Number

229961-08-4
Formula Weight

1422.72
Molecular Formula

C64H103N21O14S1
Purity

>98% (HPLC)
Solubility

?H2O : ≥ 100 mg/mL (70.29 mM)
SMILES

———
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Pisarenko OI, et al. Effects of structural analogues of apelin-12 in acute myocardial infarction in rats. J Pharmacol Pharmacother. 2013;4(3):198-203.?

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

Product			Quantity Required*
Name *			E-mail Address *
Organization *			Phone Number
Remarks