Dauriciline

CAS No. 21446-35-5

Dauriciline( ——— )

Catalog No. M39699 CAS No. 21446-35-5

Guattegaumerine is a bisbenzylisoquinoline alkaloid with antimitotic, cytotoxic and neuroprotective activities.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Dauriciline
  • Note
    Research use only, not for human use.
  • Brief Description
    Guattegaumerine is a bisbenzylisoquinoline alkaloid with antimitotic, cytotoxic and neuroprotective activities.
  • Description
    Guattegaumerine is a bisbenzylisoquinoline alkaloid with antimitotic, cytotoxic and neuroprotective activities.
  • In Vitro
    Guattegaumerine (1.25-6.25 μM; 24 hours; 30 min before exposure to serum-starvation+H2O2) significantly increases cell viability at 1.25 and 2.5μM; and guattegaumerine pretreatment significantly inhibits LDH efflux.Guattegaumerine (2.5 μM; 24 hours; 30 min before exposure to serum-starvation+H2O2) markedly reduces the oxidative stress-induced apoptosis in rat cortical neurons when compares with the control group.Guattegaumerine (1.25-2.5 μM; 24 hours; 30 min before exposure to serum-starvation+H2O2) decreases H2O2 and KCl induced Ca[2+]i increase in cortical neurons.
  • In Vivo
    ———
  • Synonyms
    ———
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ———
  • Research Area
    ———
  • Indication
    ———

Chemical Information

  • CAS Number
    21446-35-5
  • Formula Weight
    596.724
  • Molecular Formula
    C36H40N2O6
  • Purity
    >98% (HPLC)
  • Solubility
    ———
  • SMILES
    ———
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Qing Lü, et al. Guattegaumerine protects primary cultured cortical neurons against oxidative stress injury induced by hydrogen peroxide concomitant with serum deprivation. Cell Mol Neurobiol. 2009 May;29(3):355-64.?
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