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β-Cembrenediol

CAS No. 57605-81-9

β-Cembrenediol( ——— )

Catalog No. M39598 CAS No. 57605-81-9

β-Cembrenediol is a potent and orally active anticancer agent. β-Cembrenediol shows phytotoxic activities. β-Cembrenediol reduces the migration and colony formation. β-Cembrenediol decreases the protein expression of TDO2, IDO1. β-Cembrenediol has the potential for the research of prostate cancer.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    β-Cembrenediol
  • Note
    Research use only, not for human use.
  • Brief Description
    β-Cembrenediol is a potent and orally active anticancer agent. β-Cembrenediol shows phytotoxic activities. β-Cembrenediol reduces the migration and colony formation. β-Cembrenediol decreases the protein expression of TDO2, IDO1. β-Cembrenediol has the potential for the research of prostate cancer.
  • Description
    β-Cembrenediol is a potent and orally active anticancer agent. β-Cembrenediol shows phytotoxic activities. β-Cembrenediol reduces the migration and colony formation.
  • In Vitro
    Western Blot Analysis Cell Line:PC-3M cells Concentration:5, 10, 20 μM Incubation Time:48 h Result:Decreased the protein expression of TDO2, IDO1 in a dose-dependent manner.
  • In Vivo
    Animal Model:Male athymic nude mice (PC-3M PC cells) Dosage:15 mg/kg Administration:P.o.; daily for 8 weeks Result:Significantly suppressed the development, extended the latency, and delayed the onset of the locoregional PC-3M cell tumor recurrence, reduced mice plasma total prostate-specific antigen and plasma kynurenine level.
  • Synonyms
    ———
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ———
  • Research Area
    ———
  • Indication
    ———

Chemical Information

  • CAS Number
    57605-81-9
  • Formula Weight
    306.49
  • Molecular Formula
    C20H34O2
  • Purity
    >98% (HPLC)
  • Solubility
    ———
  • SMILES
    ———
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ren X, et al. Isolation, Identification, and Autotoxicity Effect of Allelochemicals from Rhizosphere Soils of Flue-Cured Tobacco. J Agric Food Chem. 2015 Oct 21;63(41):8975-80. ?
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