3-O-β-D-xylopyranosyl-(1→3)-β-D-glucuronopyranosyl-medicagenic acid 28-O-β-D-xylcopyranosyl-(1→4)-a-L-rhamnopyranosyl-(1 →2)-β-D-fucopyranosyl ester

2-Amino-6-cyclopropylamino-9H-purine,the key intermediate of abacavir was synthesized from ethyl cyanoacetate by nitrosation,cyclization with guanidine hydrochloride in the presence of EtONa and reduction to give 2,4,5-triamino-6-hydroxypyrimidine.

CTX-0294885 is a a novel bisanilino pyrimidine; exhibits inhibitory activity against a broad range of kinases in vitro.