Met-Enkephalin-Arg-Phe is a naturally occurring heptapeptide with analgesic activity.

Levothyroxine, the major hormone derived from the thyroid gland, is the agonist of Thyroid hormone receptor alpha and beta.evothyroxine (L-T(4))can upregulate the expression of P-gp mRNA and protein in LS180 cells, but only L-T(4) and L-T(3) can produce the same effect in Caco-2 cells, which are relatively lacking in PXR.

Isoferulic acid is an effective natural antioxidant in both lipid and aqueous media, it may be a new promising anti-glycation agent for the prevention of diabetic complications via inhibition of advanced glycation end products (AGEs) formation and oxidation-dependent protein damage.