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Daurinoline
CAS No. 2831-75-6
Daurinoline( ——— )
Catalog No. M39467 CAS No. 2831-75-6
Daurinoline is an alkaloid that can be isolated from the roots of Menispermum dauricum. Daurinoline may be a potential anti-tumor agent or chemosensitizer for chemo-resistant NSCLC research.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 588 | In Stock |
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| 25MG | Get Quote | In Stock |
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| 50MG | Get Quote | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameDaurinoline
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NoteResearch use only, not for human use.
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Brief DescriptionDaurinoline is an alkaloid that can be isolated from the roots of Menispermum dauricum. Daurinoline may be a potential anti-tumor agent or chemosensitizer for chemo-resistant NSCLC research.
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DescriptionDaurinoline is a non-competitive antagonist, it exerts marked relaxation effect on basilar artery of rabbits through non-competitive antagonism, it would have a protective function on microcirculation of cerebral pia mater, which may be beneficial to relieve cerebral ischemic injury.
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In VitroDaurinoline inhibits the proliferation, migration, invasion and EMT phenotype of chemo-resistant NSCLC cells.
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In Vivo———
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Synonyms———
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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Recptor5-HT Receptor; Calcium Channel; Histamine Receptor
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Research Area———
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Indication———
Chemical Information
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CAS Number2831-75-6
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Formula Weight610.74
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Molecular FormulaC37H42N2O6
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Purity>98% (HPLC)
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Solubility———
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SMILES———
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Dan-Dan Li, et al. Daurinoline suppressed the migration and invasion of chemo-resistant human non-small cell lung cancer cells by reversing EMT and Notch-1 and sensitized the cells to Taxol. Environ Toxicol Pharmacol. 2019 Feb;66:109-115.?
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