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(22E)-Ergosta-4,6,8(14),22-tetraen-3-one
CAS No. 19254-69-4
(22E)-Ergosta-4,6,8(14),22-tetraen-3-one( ——— )
Catalog No. M39405 CAS No. 19254-69-4
Ergosta-4,6,8(14),22-tetraen-3-one (compound 2) is a ergosteroid is isolated from the fruiting bodies of ganoderma applanatum.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product Name(22E)-Ergosta-4,6,8(14),22-tetraen-3-one
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NoteResearch use only, not for human use.
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Brief DescriptionErgosta-4,6,8(14),22-tetraen-3-one (compound 2) is a ergosteroid is isolated from the fruiting bodies of ganoderma applanatum.
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DescriptionErgosta-4,6,8(14),22-tetraen-3-one has cytotoxic activity against human gastric cancer cell, it can induce G2/M cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells, these results would be useful for the further utilization of many medicinal fungi in cancer treatment.
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In Vitro———
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In Vivo———
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Synonyms———
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PathwayAngiogenesis
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TargetBcl-2
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RecptorBcl-2; p53; Caspase
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Research Area———
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Indication———
Chemical Information
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CAS Number19254-69-4
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Formula Weight392.62
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Molecular FormulaC28H40O
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Purity>98% (HPLC)
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SolubilityDMSO : 20 mg/mL (50.94 mM; ultraphonic; )
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SMILES———
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Gan KH, et al. Steroidal constituents of ganoderma applanatum and ganodermaneo-japonicum. J Nat Prod. 1998 Nov;61(11):1421-2.?
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