(R)-Nepicastat HCl, the R-enantiomer of Nepicastat HCl, is a potent and selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine-β-hydroxylase, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors.

Secretoneurin, rat, a 33-amino acid polypeptide, is generated by proteolytic processing of secretogranin II (SgII).

Protease K is a nonspecific serine protease that is useful for general digestion of proteins.?It is active in the presence of SDS or urea and over a wide range of pH (4-12), salt concentrations, and temperatures.