Borofalan echibits antineoplastic effects. Borofalan can be used in studies on recurrent or locally advanced head and neck cancer.

Gypenoside XLVI shows strong cytotoxic activity against A549 cells, with the IC50 values of 52.63±8.31 ug/ml.

PF-03049423 is a potent and highly selective phosphodiesterase-5A inhibitor with an IC50 of approximately 0.2 nM for rat and human thrombomodulin.