Methyl nicotinate is the methyl ester of that is used as an active ingredient as a rubefacient in over-the-counter topical preparations indicated for muscle and joint pain.?The action of methyl nicotinate as a rubefacient is thought to involve peripheral vasodilation.

GSK2850163 is a novel inhibitor of inositol-requiring enzyme-1 alpha (IRE1α) which can inhibit RNase activity and IRE1α kinase activity (IC50s: 200 and 20 nM).

Varespladib methyl, a bioavailable prodrug of Varespladib, is a selective group II secretory phospholipase A2 inhibitor.