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Norswertianin

CAS No. 22172-15-2

Norswertianin( ——— )

Catalog No. M38789 CAS No. 22172-15-2

Norswertianin, a xanthone compound, serves as a powerful anti-glioma compound. Norswertianin induces GBM cells differentiation through oxidative stress and Akt/mTOR dependent autophagy.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Norswertianin
  • Note
    Research use only, not for human use.
  • Brief Description
    Norswertianin, a xanthone compound, serves as a powerful anti-glioma compound. Norswertianin induces GBM cells differentiation through oxidative stress and Akt/mTOR dependent autophagy.
  • Description
    Norswertianin, a xanthone compound, serves as a powerful anti-glioma compound. Norswertianin induces GBM cells differentiation through oxidative stress and Akt/mTOR dependent autophagy.
  • In Vitro
    Norswertianin (12.5-50 μM; 48 hours) stimulats expression of GFAP and β-tubulin in U251 cells.Norswertianin (40 μM; 48 hours) causes the appearance of elongated processes in U251 cells, associated with G2/M cell cycle arrest.Norswertianin (40 μM; 48 hours) exhibits an increase in intracellular acidification and LC3 conversion.
  • In Vivo
    ———
  • Synonyms
    ———
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ———
  • Research Area
    ———
  • Indication
    ———

Chemical Information

  • CAS Number
    22172-15-2
  • Formula Weight
    260.2
  • Molecular Formula
    C13H8O6
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 13 mg/mL (49.96 mM; ultraphonic )
  • SMILES
    ———
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Gordana Tovilovic-Kovacevic, et al. Xanthone-rich extract from Gentiana dinarica transformed roots and its active component norswertianin induce autophagy and ROS-dependent differentiation of human glioblastoma cell line. Phytomedicine?
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