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Norswertianin
CAS No. 22172-15-2
Norswertianin( ——— )
Catalog No. M38789 CAS No. 22172-15-2
Norswertianin, a xanthone compound, serves as a powerful anti-glioma compound. Norswertianin induces GBM cells differentiation through oxidative stress and Akt/mTOR dependent autophagy.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 1408 | In Stock |
|
| 50MG | Get Quote | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameNorswertianin
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NoteResearch use only, not for human use.
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Brief DescriptionNorswertianin, a xanthone compound, serves as a powerful anti-glioma compound. Norswertianin induces GBM cells differentiation through oxidative stress and Akt/mTOR dependent autophagy.
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DescriptionNorswertianin, a xanthone compound, serves as a powerful anti-glioma compound. Norswertianin induces GBM cells differentiation through oxidative stress and Akt/mTOR dependent autophagy.
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In VitroNorswertianin (12.5-50 μM; 48 hours) stimulats expression of GFAP and β-tubulin in U251 cells.Norswertianin (40 μM; 48 hours) causes the appearance of elongated processes in U251 cells, associated with G2/M cell cycle arrest.Norswertianin (40 μM; 48 hours) exhibits an increase in intracellular acidification and LC3 conversion.
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In Vivo———
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Synonyms———
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PathwayOthers
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TargetOther Targets
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Recptor———
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Research Area———
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Indication———
Chemical Information
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CAS Number22172-15-2
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Formula Weight260.2
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Molecular FormulaC13H8O6
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Purity>98% (HPLC)
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SolubilityDMSO : 13 mg/mL (49.96 mM; ultraphonic )
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SMILES———
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Gordana Tovilovic-Kovacevic, et al. Xanthone-rich extract from Gentiana dinarica transformed roots and its active component norswertianin induce autophagy and ROS-dependent differentiation of human glioblastoma cell line. Phytomedicine?
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