Capsiate

CAS No. 205687-01-0

Capsiate( ——— )

Catalog No. M38741 CAS No. 205687-01-0

Capsiate, as a capsaicin analogue extracted from a non-pungent cultivar of CH-19 sweet red pepper, is an orally active agonist of TRPV1.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Capsiate
  • Note
    Research use only, not for human use.
  • Brief Description
    Capsiate, as a capsaicin analogue extracted from a non-pungent cultivar of CH-19 sweet red pepper, is an orally active agonist of TRPV1.
  • Description
    Capsiate is a non-pungent analogue of capsaicin with a similar biological profile. It has a role as an anti-allergic agent, a plant metabolite, an antioxidant, an angiogenesis inhibitor, a hypoglycemic agent, an anti-inflammatory agent and a capsaicin receptor agonist.
  • In Vitro
    Capsiate evokes current responses in HEK293 cells expressing TRPV1.
  • In Vivo
    Capsiate does not exhibit irritancy-related effects on the oral cavity or eye.Capsiate (0.03~0.54 mM; s.c.) induces nociceptive responses in mice.Animal Model:Male ddY-strain mice (20–24 g) Dosage:0.5 or 5 mM Administration:P.o.Result:Did not cause pungency-related behaviors.
  • Synonyms
    ———
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ———
  • Indication
    ———

Chemical Information

  • CAS Number
    205687-01-0
  • Formula Weight
    306.4
  • Molecular Formula
    C18H26O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 100 mg/mL (326.37 mM; ultraphonic; )
  • SMILES
    C(OC(CCCC/C=C/C(C)C)=O)C1=CC(OC)=C(O)C=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Iida T, et al. TRPV1 activation and induction of nociceptive response by a non-pungent capsaicin-like compound, capsiate. Neuropharmacology. 2003;44(7):958-967.?
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