Acetylcorynoline may be one of the potent immunosuppressive agents through the blockage of dendritic cells maturation and function.

Complanatin I is a natural product that can be isolated from Astragalus complanatus.

Apelin biased agonist; exhibits bias for the G protein pathway. Stimulates endothelial NOS phosphorylation and expression, promotes proliferation, and attenuates apoptosis of human pulmonary arterial endothelial cells in vitro. Shows positive inotropic and vasodilatory effects in vivo and improves cardiac structure and function in a model of pulmonary arterial hypertension.