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4-(Benzo[d]oxazol-2-yl)aniline

CAS No. 20934-81-0

4-(Benzo[d]oxazol-2-yl)aniline( —— )

Catalog No. M37932 CAS No. 20934-81-0

4-(Benzo[d]oxazol-2-yl)aniline is a potent antitumor agent with inhibitory activity against mammary carcinoma cell lines .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    4-(Benzo[d]oxazol-2-yl)aniline
  • Note
    Research use only, not for human use.
  • Brief Description
    4-(Benzo[d]oxazol-2-yl)aniline is a potent antitumor agent with inhibitory activity against mammary carcinoma cell lines .
  • Description
    4-(Benzo[d]oxazol-2-yl)aniline is a potent antitumor agent. 4-(Benzo[d]oxazol-2-yl)aniline has inhibitory activity against mammary carcinoma cell lines.
  • In Vitro
    4-(Benzo[d]oxazol-2-yl)aniline (compound 5b) (0-100 μM; 7 days for MCF-7 and 10 days for MDA 468) has inhibitory activity against MCF-7 and MDA 468 mammary carcinoma cell lines.Cell Proliferation Assayv Cell Line:MCF-7 and MDA 468v Concentration:0-100 μMvv Incubation Time:7 days for MCF-7 and 10 days for MDA 468 Result:Exhibited inhibitory activity against MCF-7 (IC50>0.01-0.1 μM) and MDA 468 (IC50>0.1-1 μM).
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    20934-81-0
  • Formula Weight
    210.23
  • Molecular Formula
    C13H10N2O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : ≥ 100 mg/mL (475.67 mM)
  • SMILES
    NC1=CC=C(C=C1)C1=NC2=CC=CC=C2O1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Shi DF, et al. Antitumor benzothiazoles. 3. Synthesis of 2-(4-aminophenyl)benzothiazoles and evaluation of their activities against breast cancer cell lines in vitro and in vivo. J Med Chem. 1996 Aug 16;39(17):3375-84.?
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