2-C-beta-Methylguanosine

CAS No. 374750-30-8

2-C-beta-Methylguanosine( —— )

Catalog No. M37882 CAS No. 374750-30-8

2'-C-beta-Methylguanosine (2'-C-Methylguanosine) is a metabolite of the hepatitis C virus nucleotide polymerase inhibitor, BMS-986094, which has antiviral activity and inhibits dengue virus 2.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 459 In Stock
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Biological Information

  • Product Name
    2-C-beta-Methylguanosine
  • Note
    Research use only, not for human use.
  • Brief Description
    2'-C-beta-Methylguanosine (2'-C-Methylguanosine) is a metabolite of the hepatitis C virus nucleotide polymerase inhibitor, BMS-986094, which has antiviral activity and inhibits dengue virus 2.
  • Description
    2'-C-Methylguanosine (2'-C-beta-Methylguanosine) is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    Antiviral
  • Recptor
    Antiviral
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    374750-30-8
  • Formula Weight
    297.27
  • Molecular Formula
    C11H15N5O5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C[C@]1(O)[C@H](N2C3=C(N=C2)C(=O)N=C(N)N3)O[C@H](CO)[C@H]1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.?
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