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2-O-Methyl-2-thiouridine

CAS No. 113886-72-9

2-O-Methyl-2-thiouridine( —— )

Catalog No. M37880 CAS No. 113886-72-9

2'-O-Methyl-2-thiouridine is a purine nucleoside analogue present in synthetic thermophilic bacterial tRNAs. 2'-O-Methyl-2-thiouridine is more selective for A than unmodified U.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    2-O-Methyl-2-thiouridine
  • Note
    Research use only, not for human use.
  • Brief Description
    2'-O-Methyl-2-thiouridine is a purine nucleoside analogue present in synthetic thermophilic bacterial tRNAs. 2'-O-Methyl-2-thiouridine is more selective for A than unmodified U.
  • Description
    2’-O-Methyl-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Antibiotic
  • Recptor
    Nucleoside Antimetabolite/Analog
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    113886-72-9
  • Formula Weight
    274.29
  • Molecular Formula
    C10H14N2O5S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O(C)[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=S)NC(=O)C=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.?
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