5-Hydroxyuridine

CAS No. 957-77-7

5-Hydroxyuridine( —— )

Catalog No. M37873 CAS No. 957-77-7

5-Hydroxyuridine (OHUrd) is a purine nucleoside analogue with potential antitumor activity, demonstrating cytotoxicity against human colon adenocarcinoma cell lines.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 33 In Stock
10MG 46 In Stock
25MG 75 In Stock
50MG 105 In Stock
100MG 176 In Stock
200MG Get Quote In Stock
500MG 440 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    5-Hydroxyuridine
  • Note
    Research use only, not for human use.
  • Brief Description
    5-Hydroxyuridine (OHUrd) is a purine nucleoside analogue with potential antitumor activity, demonstrating cytotoxicity against human colon adenocarcinoma cell lines.
  • Description
    5-Hydroxyuridine (OHUrd) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Antibiotic
  • Recptor
    Nucleoside Antimetabolite/Analog
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    957-77-7
  • Formula Weight
    260.2
  • Molecular Formula
    C9H12N2O7
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (480.40 mM; Ultrasonic )
  • SMILES
    O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)NC(=O)C(O)=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.?
molnova catalog
related products
  • Benznidazole

    Benznidazole has an antiprotozoal activity by interfering with parasite protein biosynthesis influencing cytokines production and stimulating host phagocytosis.

  • (2E)-3-(1,3-Benzodio...

    (2E)-3-(1,3-Benzodioxol-5-yl)-2-propenoic acid displays EC50 values of 73.5 μM against T. cruzi. trypomastigotes.

  • L-Uridine

    L-Uridine is the enantiomer of D-uridine, a nucleoside that acts as a phosphate acceptor for nucleoside phosphotransferase, in the normal RNA component of a normal RNA isolated from Polyporaceae fungus Poria cocos (Schw.) L-Uridine has potential antiviral activity.