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Venuloside A

CAS No. 1609278-97-8

Venuloside A( —— )

Catalog No. M37862 CAS No. 1609278-97-8

Venuloside A (ESK246), a monoprostane glycoside from Pittosporum venulosum, is a LAT3 inhibitor and a leucine uptake inhibitor that inhibits the transporter of leucine through LAT3, and may be used in the study of prostate cancer.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Venuloside A
  • Note
    Research use only, not for human use.
  • Brief Description
    Venuloside A (ESK246), a monoprostane glycoside from Pittosporum venulosum, is a LAT3 inhibitor and a leucine uptake inhibitor that inhibits the transporter of leucine through LAT3, and may be used in the study of prostate cancer.
  • Description
    Venuloside A is a potent inhibitor of LAT3. Venuloside A inhibits the leucine uptake in LNCaP prostate cancer cells with an IC50 of 8.12 μM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    transporter
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1609278-97-8
  • Formula Weight
    424.53
  • Molecular Formula
    C23H36O7
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O(C(C)(C)[C@@H]1CCC(C)=CC1)[C@H]2[C@H](OC(C)=O)[C@@H](OC(C=C(C)C)=O)[C@@H](O)[C@@H](C)O2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Wang Q, et al. Monoterpene glycoside ESK246 from Pittosporum targets LAT3 amino acid transport and prostate cancer cell growth. ACS Chem Biol. 2014 Jun 20;9(6):1369-76.?
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