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Lactic acid
CAS No. 50-21-5
Lactic acid( —— )
Catalog No. M37801 CAS No. 50-21-5
Lactic acid (2-hydroxypropanoic acid) is a product of glycolysis and is widely found in nature.Lactic acid is produced in the body during hypoxia in contracted skeletal muscle and can be removed under fully aerobic conditions.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 28 | In Stock |
|
| 100MG | 37 | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | 60 | In Stock |
|
| 1G | 75 | In Stock |
|
Biological Information
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Product NameLactic acid
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NoteResearch use only, not for human use.
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Brief DescriptionLactic acid (2-hydroxypropanoic acid) is a product of glycolysis and is widely found in nature.Lactic acid is produced in the body during hypoxia in contracted skeletal muscle and can be removed under fully aerobic conditions.
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DescriptionLactate (Lactic acid) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactate is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactate is an oncometabolite and has immune protective role of lactate in anti-tumor immunity.
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In VitroCell Proliferation Assay Cell Line:Uveal melanoma 92.1 cells Concentration:20 mM Incubation Time:24, 48 h Result:Inhibited cell proliferation and migration.Western Blot Analysis Cell Line:Uveal melanoma cells Concentration:20 mM Incubation Time:24 h Result:Showed an increase in the protein expression levels of MCT1 and HCAR1 Western Blot Analysis Cell Line:Uveal melanoma cells Concentration:20 mM Incubation Time:24 h Result:Induced a significant increase in mRNA expression levels of SLC16A1 and HCAR1.
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In VivoAnimal Model:Female C57BL/6 mice with MC38 colon cancer cells Dosage:1.6 g/kg Administration:Subcutaneous; daily from Day 8 to 30 days Result:Significantly suppressed tumor growth.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number50-21-5
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Formula Weight90.08
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Molecular FormulaC3H6O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?H2O : 100 mg/mL (1110.12 mM; Ultrasonic) DMSO : 100 mg/mL (1110.12 mM; Ultrasonic )
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SMILESCC(O)C(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Lucia Longhitano, et al. Lactate Rewrites the Metabolic Reprogramming of Uveal Melanoma Cells and Induces Quiescence Phenotype. Int J Mol Sci. 2022 Dec 20;24(1):24.?
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