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(S,S)-Secoisolariciresinol diglucoside
CAS No. 257930-74-8
(S,S)-Secoisolariciresinol diglucoside( —— )
Catalog No. M37778 CAS No. 257930-74-8
(S,S)-Secoisolariciresinol diglucoside ((S,S)-SDG) is a lignan present in flaxseed with anti-inflammatory, antioxidant, anti-microbial and neuroprotective properties and can be used in the study of obesity, arthritis and osteoporosis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 48 | In Stock |
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| 5MG | 77 | In Stock |
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| 10MG | 133 | In Stock |
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| 25MG | 256 | In Stock |
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| 50MG | 356 | In Stock |
|
| 100MG | 609 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name(S,S)-Secoisolariciresinol diglucoside
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NoteResearch use only, not for human use.
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Brief Description(S,S)-Secoisolariciresinol diglucoside ((S,S)-SDG) is a lignan present in flaxseed with anti-inflammatory, antioxidant, anti-microbial and neuroprotective properties and can be used in the study of obesity, arthritis and osteoporosis.
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DescriptionSecoisolariciresinol diglucoside ((S,S)-SDG), the main lignan in wholegrain flaxseed, is known for its beneficial effects including anti-inflammatory, antioxidant, anti-mutagenic, anti-microbial, anti-obesity, hypolipidemic, and neuroprotective effects.
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In VitroSecoisolariciresinol diglucoside (1-500 μM) possesses strong reducing power and high free radical scavenging activity for hydroxyl, peroxyl and DPPH free radicals.Secoisolariciresinol diglucoside (1-50 μM; 24 h) attenuates human monocyte adhesion to and migration across human brain endothelial monolayers.
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In VivoSecoisolariciresinol diglucoside (4 mg/mouse; a single p.o.) diminishes leukocyte adhesion and migration across blood-brain barrier (BBB) in neuroinflammation.Animal Model:Hand feeding mice (10 weeks old, male) are injected with TNFα Dosage:4 mg/mouse Administration:P.o. 2 h before i.c. administration of TNFα Result:Attenuated adhesion of leukocytes to the endothelium by 50% and attenuated migration of leukocytes across the BBB by 64%.
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Synonyms——
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PathwayOthers
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TargetAntioxidant
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RecptorAntioxidant
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Research Area——
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Indication——
Chemical Information
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CAS Number257930-74-8
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Formula Weight686.7
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Molecular FormulaC32H46O16
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Purity>98% (HPLC)
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SolubilityIn Vitro:?H2O : ≥ 100 mg/mL (145.62 mM)
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SMILES[C@@H]([C@H](CC1=CC(OC)=C(O)C=C1)CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)(CC3=CC(OC)=C(O)C=C3)CO[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Mishra OP, et al. Synthesis and antioxidant evaluation of (S,S)- and (R,R)-secoisolariciresinol diglucosides (SDGs). Bioorg Med Chem Lett. 2013 Oct 1;23(19):5325-8.?
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