Cart
sales@molnova.com
Home - Products - Others - Other Targets - AGI-43192

AGI-43192

CAS No. 2377491-54-6

AGI-43192( —— )

Catalog No. M37655 CAS No. 2377491-54-6

AGI-43192 is a potent methionine adenosine transferase 2A (MAT2A) inhibitor that penetrates the blood-brain barrier.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 105 Get Quote
5MG 164 Get Quote
10MG 263 Get Quote
25MG 420 Get Quote
50MG 591 Get Quote
100MG 772 Get Quote
500MG 1557 Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    AGI-43192
  • Note
    Research use only, not for human use.
  • Brief Description
    AGI-43192 is a potent methionine adenosine transferase 2A (MAT2A) inhibitor that penetrates the blood-brain barrier.
  • Description
    AGI-43192 is a potent inhibitor of methionine adenosyltransferase 2A (MAT2A). AGI-43192 is a potent, but limited brain-penetrant compound. AGI-43192 has the potential for exploring the effects of SAM modulation in the central nervous system (CNS) and research of cancer disease.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2377491-54-6
  • Formula Weight
    484.86
  • Molecular Formula
    C23H16ClF3N6O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 13.89 mg/mL (28.65 mM; Ultrasonic (<60°C)
  • SMILES
    Cn1cc2cc(ccc2n1)-n1cc2cnc(NCC(F)(F)F)nc2c(-c2ccc(Cl)cc2)c1=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Li M, et al. Leveraging Structure-Based Drug Design to Identify Next-Generation MAT2A Inhibitors, Including Brain-Penetrant and Peripherally Efficacious Leads. J Med Chem. 2022;65(6):4600-4615.?
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • trans-2-Undecenoic a...

    trans-2-Undecenoic acid ((E)-2-Undecenoic acid) is an α,β-unsaturated carboxylic acid and is characterized by acid dimers.

  • 1F-fructofuranosylny...

    1F-Fructofuranosylnystose is a kind of Fructooligosaccharides which are naturally occurring sugars with potentially beneficial nutritional effects.

  • AG1024

    AG-1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM), and is less potent for IR(IC50=57 μM).

Sign In Join Free