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AGI-43192
CAS No. 2377491-54-6
AGI-43192( —— )
Catalog No. M37655 CAS No. 2377491-54-6
AGI-43192 is a potent methionine adenosine transferase 2A (MAT2A) inhibitor that penetrates the blood-brain barrier.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 181 | In Stock |
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| 5MG | 164 | In Stock |
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| 10MG | 263 | In Stock |
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| 25MG | 434 | In Stock |
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| 50MG | 597 | In Stock |
|
| 100MG | 798 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 1609 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAGI-43192
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NoteResearch use only, not for human use.
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Brief DescriptionAGI-43192 is a potent methionine adenosine transferase 2A (MAT2A) inhibitor that penetrates the blood-brain barrier.
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DescriptionAGI-43192 is a potent inhibitor of methionine adenosyltransferase 2A (MAT2A). AGI-43192 is a potent, but limited brain-penetrant compound. AGI-43192 has the potential for exploring the effects of SAM modulation in the central nervous system (CNS) and research of cancer disease.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number2377491-54-6
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Formula Weight484.86
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Molecular FormulaC23H16ClF3N6O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 13.89 mg/mL (28.65 mM; Ultrasonic (<60°C)
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SMILESCn1cc2cc(ccc2n1)-n1cc2cnc(NCC(F)(F)F)nc2c(-c2ccc(Cl)cc2)c1=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Li M, et al. Leveraging Structure-Based Drug Design to Identify Next-Generation MAT2A Inhibitors, Including Brain-Penetrant and Peripherally Efficacious Leads. J Med Chem. 2022;65(6):4600-4615.?
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