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PY-60

CAS No. 2765218-56-0

PY-60( —— )

Catalog No. M37636 CAS No. 2765218-56-0

PY-60 can effectively activate YAP transcriptional activity against annexin A2 (ANXA2) (Kd value of 1.4 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 128 In Stock
5MG 117 In Stock
10MG 187 In Stock
25MG 376 In Stock
50MG 529 In Stock
100MG 731 In Stock
200MG 1004 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    PY-60
  • Note
    Research use only, not for human use.
  • Brief Description
    PY-60 can effectively activate YAP transcriptional activity against annexin A2 (ANXA2) (Kd value of 1.4 μM).
  • Description
    PY-60 is a robust and specific activator of YAP transcriptional activity that targets annexin A2 (ANXA2) with a Kd of 1.4 μM. PY-60 directly binds to ANXA2 and antagonizes its normal cellular function of repressing YAP activity.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    YAP | Annexin A
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2765218-56-0
  • Formula Weight
    313.37
  • Molecular Formula
    C16H15N3O2S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (319.11 mM; Ultrasonic )
  • SMILES
    C(NCCCC1=NC=CS1)(=O)C=2C=C(ON2)C3=CC=CC=C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Shalhout SZ, et al. YAP-dependent proliferation by a small molecule targeting annexin A2. Nat Chem Biol. 2021;17(7):767-775.?
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