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(rac)-Exatecan Intermediate 1
CAS No. 102978-40-5
(rac)-Exatecan Intermediate 1( —— )
Catalog No. M37604 CAS No. 102978-40-5
(rac)-Exatecan Intermediate 1 is a camptothecin derivative, a potential topoisomerase I inhibitor, used in tumor research.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 29 | In Stock |
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| 10MG | 41 | In Stock |
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| 25MG | 69 | In Stock |
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| 50MG | 108 | In Stock |
|
| 100MG | 174 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product Name(rac)-Exatecan Intermediate 1
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NoteResearch use only, not for human use.
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Brief Description(rac)-Exatecan Intermediate 1 is a camptothecin derivative, a potential topoisomerase I inhibitor, used in tumor research.
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Description(rac)-Exatecan Intermediate 1 is an isomer of Exatecan Intermediate 1 (HY-42487). Exatecan Intermediate 1 (compound 6) is an intermediate of Exatecan (HY-13631), a camptothecin-based anticancer agent. Exatecan inhibits tumor growth by interfering with the proliferation and division of tumor cells by interacting with DNA. Exatecan is primarily used in research into a variety of cancers including ovarian, lung and breast cancer.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAntibody Drug Conjugates (ADC)
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TargetADC Cytotoxin
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RecptorADC Cytotoxin | Topoisomerase
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Research Area——
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Indication——
Chemical Information
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CAS Number102978-40-5
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Formula Weight263.25
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Molecular FormulaC13H13NO5
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C1C2=C(C=C3C(=O)CCN13)C(O)(C(=O)OC2)CC
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Weng W, et al. Antibody-Exatecan Conjugates with a Novel Self-immolative Moiety Overcome Resistance in Colon and Lung Cancer. Cancer Discov. 2023 Apr 3;13(4):950-973.?
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