SARS-CoV-2 3CLpro-IN-16

CAS No. 352659-40-6

SARS-CoV-2 3CLpro-IN-16( —— )

Catalog No. M37246 CAS No. 352659-40-6

SARS-CoV-2 3CLpro-IN-16 is a covalent inhibitor of SARS-CoV-2 3CLpro activity, exerting its effect by forming a covalent bond with Cys145.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 459 In Stock
10MG 657 In Stock
25MG 1026 In Stock
50MG 1386 In Stock
100MG 1832 In Stock
200MG Get Quote In Stock
500MG 3655 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    SARS-CoV-2 3CLpro-IN-16
  • Note
    Research use only, not for human use.
  • Brief Description
    SARS-CoV-2 3CLpro-IN-16 is a covalent inhibitor of SARS-CoV-2 3CLpro activity, exerting its effect by forming a covalent bond with Cys145.
  • Description
    SARS-CoV-2 3CLpro-IN-16 (Compound 3a) is a covalent SARS-CoV-2 3CLpro inhibitor (IC50s: 2.124 μM). SARS-CoV-2 3CLpro-IN-16 binds to the active site and forms a covalent bond with Cys145 of 3CLpro.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    SARS-CoV
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    352659-40-6
  • Formula Weight
    294.37
  • Molecular Formula
    C17H14N2OS
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    N#CSCC(=O)N1C=2C=CC=CC2CCC=3C=CC=CC31
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ren P, et al. Discovery and Mechanism Study of SARS-CoV-2 3C-like Protease Inhibitors with a New Reactive Group. J Med Chem. 2023 Aug 18.?
molnova catalog
related products
  • Methyl 4-prenyloxyci...

    Methyl 4-prenyloxycinnamate is a Phenylpropanoids product that can be isolated from the barks of Cinnamomum cassia.

  • Cathepsin S substrat...

    Ac-KQKLR-AMC (Cathepsin S substrate) is a biological active peptide. (Cathepsins are a class of globular lysosomal proteases, playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin S is a cysteine proteinase involved in the pathogenesis of autoimmune diseases, atherosclerosis, cancer, obesity and related diseases.This peptide is a cathepsin S substrate fluorescently labeled with AMC (Ex/Em=354 nm/442 nm). It can be used to measure cathepsin S activity.)

  • Adamantane

    The adamantane moiety is the structural backbone of numerous compounds and the physicochemical and biological properties of organic polyhedral compounds with practical application in the pharmaceutical industry.