Mal-amide-PEG8-Val-Ala-PAB-PNP

CAS No. 2210247-59-7

Mal-amide-PEG8-Val-Ala-PAB-PNP( —— )

Catalog No. M37128 CAS No. 2210247-59-7

Mal-amide-PEG8-Val-Ala-PAB-PNP is a cleavable linker used in the production of antibody-drug conjugates (ADCs), enabling the attachment of cytotoxic drugs to antibodies for targeted delivery .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 186 In Stock
10MG 282 In Stock
25MG 566 In Stock
50MG 918 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Mal-amide-PEG8-Val-Ala-PAB-PNP
  • Note
    Research use only, not for human use.
  • Brief Description
    Mal-amide-PEG8-Val-Ala-PAB-PNP is a cleavable linker used in the production of antibody-drug conjugates (ADCs), enabling the attachment of cytotoxic drugs to antibodies for targeted delivery .
  • Description
    Mal-amide-PEG8-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Antibody Drug Conjugates (ADC)
  • Target
    ADCs Linker/Click Chemistry
  • Recptor
    ADC Linker
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2210247-59-7
  • Formula Weight
    1033.08
  • Molecular Formula
    C48H68N6O19
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    N(C([C@@H](NC([C@@H](NC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN1C(=O)C=CC1=O)=O)=O)C(C)C)=O)C)=O)C2=CC=C(COC(OC3=CC=C(N(=O)=O)C=C3)=O)C=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Junutula JR, et, al. Preparation of isoquinolidinobenzodiazepines and antibody conjugates thereof for treatment of hematological malignancies and solid tumors. WO2018053552
molnova catalog
related products
  • Hydroxy-PEG4-(CH2)2-...

    Hydroxy-PEG4-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG4-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 191).

  • Biotin-PEG3-SS-azide

    Biotin-PEG3-SS-azide (Biotin-PEG3-amido-SS-amido-azide) is a cleavable ADC linker containing 3-unit PEG and can be used to synthesize antibody-drug conjugates (ADCs).

  • DBCO acid 3

    DBCO acid 3 is a Click Chemistry intermidate used for antibody-drug conjugates.