Duostatin 5( —— )

Catalog No. M37127 CAS No. 2124210-34-8

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Duostatin 5
Note

Research use only, not for human use.
Brief Description

Duostatin 5 (Duo-5) is a sea hare toxin analog commonly used in the synthesis of ADC compounds.
Description

Duostatin 5 is a cytotoxin designed based on dolastatin, can meet the requirement of serving as an effective cytotoxin in ADC, but has the advantages of fewer synthesis steps, easy operation, less difficulty in quality control and more stable chemical synthesis process.
In Vitro

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In Vivo

——
Synonyms

——
Pathway

Antibody Drug Conjugates (ADC)
Target

ADC Cytotoxin
Recptor

ADC Cytotoxin
Research Area

——
Indication

——

CAS Number

2124210-34-8
Formula Weight

772.03
Molecular Formula

C40H69N9O6
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 125 mg/mL (161.91 mM; Ultrasonic )
SMILES

[C@H]([C@H](C(N[C@@H](CC1=CC=C(N)C=C1)CN=[N+]=[N-])=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@H](C(C)C)N(C)C)=O)[C@@H](C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]
Chemical Name

——

1. Toxin for antibody drug conjugate and preparation method thereof. CN107857798B.

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