Cart
sales@molnova.com
Home - Products - Angiogenesis - FAK - FAK-IN-14

FAK-IN-14

CAS No. 2766666-22-0

FAK-IN-14( —— )

Catalog No. M37125 CAS No. 2766666-22-0

FAK-IN-14 is a highly effective focal adhesion kinase (FAK) inhibitor that induces apoptosis and cell cycle arrest.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 67 Get Quote
5MG 93 Get Quote
10MG 155 Get Quote
25MG 254 Get Quote
50MG 365 Get Quote
100MG 538 Get Quote
500MG 1134 Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    FAK-IN-14
  • Note
    Research use only, not for human use.
  • Brief Description
    FAK-IN-14 is a highly effective focal adhesion kinase (FAK) inhibitor that induces apoptosis and cell cycle arrest.
  • Description
    FAK-IN-14 (compound 8d) is a focal adhesion kinase(FAK) inhibitor with an IC50 value of 0.2438 nM. FAK-IN-14 induces U87-MG cell early apoptosis and arrest the cell at the G2/M phase.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    FAK
  • Recptor
    FAK | FGFR | PYK2 | mTOR | MEK | Akt | c-Kit
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2766666-22-0
  • Formula Weight
    502.43
  • Molecular Formula
    C21H24BrN7OS
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(NC)C=1SC=CC1NC2=NC(=NC=C2Br)NC3=CC=C(C=C3)N4CCN(C)CC4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zhiwu Long, et al. Design, synthesis and biological evaluation of 4-arylamino-pyrimidine derivatives as focal adhesion kinase inhibitors. Bioorg Chem. 2023.?
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Alizarin

    Alizarin, a red dye derived from the roots of plants of the madder genus, inhibits P450 isoform CYP1A1( IC50 = 6.2 μM), CYP1A2 (IC50 =10.0 μM )and CYP1B1(IC50 = 2.7 μM).

  • Batatasin III

    Batatasin III inhibits cancer migration and invasion by suppressing epithelial to mesenchymal transition and FAK-AKT signals and possesses anti-cancer activities. Batatasin III has a long-term inhibitory effect on whole-plant growth and shows germination.

  • 2119738-71-3

    2119738-71-3

Sign In Join Free