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AChE/BuChE-IN-4

CAS No. 1997158-25-4

AChE/BuChE-IN-4( —— )

Catalog No. M37106 CAS No. 1997158-25-4

AChE/BuChE-IN-4 is a multi-target AChE/BuChE inhibitor with oral activity and blood-brain barrier permeability, with IC50 values of 2.08 and 7.41 μM for AChE and BuChE, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 159 In Stock
25MG 235 In Stock
50MG 310 In Stock
100MG 461 In Stock
200MG 624 In Stock
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Biological Information

  • Product Name
    AChE/BuChE-IN-4
  • Note
    Research use only, not for human use.
  • Brief Description
    AChE/BuChE-IN-4 is a multi-target AChE/BuChE inhibitor with oral activity and blood-brain barrier permeability, with IC50 values of 2.08 and 7.41 μM for AChE and BuChE, respectively.
  • Description
    AChE/BuChE-IN-4(compound 4a) is aorally activeandbrain-penetrantmultitarget-directedAChE/BuChEinhibitor againstAChEandBuChE, with theIC50of 2.08 and 7.41 μM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    AChE
  • Recptor
    AChE
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1997158-25-4
  • Formula Weight
    297.4
  • Molecular Formula
    C17H23N5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    N=1C=CC(=NC1N)NCC2CCN(CC=3C=CC=CC3)CC2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Concei??o RAD, et al. Structure-based design of new N-benzyl-piperidine derivatives as multitarget-directed AChE/BuChE inhibitors for Alzheimer's disease [published online ahead of print, 2023 Oct 5]. J Cell Biochem. 2023;10.1002/jcb.30483.?
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