Cart
sales@molnova.com
GPX4-IN-5
CAS No. 2922824-09-5
GPX4-IN-5( —— )
Catalog No. M37105 CAS No. 2922824-09-5
GPX4-IN-5 is a small molecule covalent GPX4 inhibitor (IC50: 0.12 μM) with antitumour activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 104 | In Stock |
|
| 5MG | 93 | In Stock |
|
| 10MG | 150 | In Stock |
|
| 25MG | 256 | In Stock |
|
| 50MG | 365 | In Stock |
|
| 100MG | 544 | In Stock |
|
| 200MG | 775 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameGPX4-IN-5
-
NoteResearch use only, not for human use.
-
Brief DescriptionGPX4-IN-5 is a small molecule covalent GPX4 inhibitor (IC50: 0.12 μM) with antitumour activity.
-
DescriptionGPX4-IN-5 (Compound C18) is a GPX4 covalent inhibitor with an IC50 value of 0.12 μM.GPX4-IN-5 (Compound C18) can induce ferroptosis for the research of triple-negative breast cancer (TNBC) .
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorGPX
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2922824-09-5
-
Formula Weight381.78
-
Molecular FormulaC18H17ClFNO5
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (261.93 mM; Ultrasonic )
-
SMILESO=C(N(C1=CC=C2OCCOC2=C1)C3=CC(OC)=C(F)C(OC)=C3)CCl
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Chen T, et al. Discovery of Novel Potent Covalent Glutathione Peroxidase 4 Inhibitors as Highly Selective Ferroptosis Inducers for the Treatment of Triple-Negative Breast Cancer. J Med Chem. 2023 Jul 27;66(14):10036-10059.
molnova catalog
related products
-
Anthranilic acid
2-Aminobenzoic acid also known as anthranilate or anthranilic acid belongs to the class of organic compounds known as aminobenzoic acids.
-
[Des-Thr5]-Glucagon
(Des-Thr5)-Glucagon is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development.
-
JMJD7-IN-1
JMJD7-IN-1 is a potent?JMJD7?inhibitor, with an?IC50?of 6.62 μM. JMJD7-IN-1 shows good inhibitory activity against cells expressing a high level of JMJD7.
