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YAP-TEAD-IN-3
CAS No. 2714434-21-4
YAP-TEAD-IN-3( —— )
Catalog No. M37083 CAS No. 2714434-21-4
YAP-TEAD-IN-3 is an inhibitor of YAP/TAZ-TEAD interactions with an IC50 of 9 nM for Avi-human TEAD (4217-434).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 744 | In Stock |
|
| 10MG | 1007 | In Stock |
|
| 50MG | 1376 | In Stock |
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| 100MG | 1841 | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameYAP-TEAD-IN-3
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NoteResearch use only, not for human use.
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Brief DescriptionYAP-TEAD-IN-3 is an inhibitor of YAP/TAZ-TEAD interactions with an IC50 of 9 nM for Avi-human TEAD (4217-434).
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DescriptionYAP-TEAD-IN-3 (compound 155) is a YAP/TAZ-TEAD inhibitor. YAP-TEAD-IN-3 inhibits Avi-humanTEAD4217-434 with an IC50 value of 9 nM. YAP-TEAD-IN-3 also inhibits NCI-H2052 with an GI50of 0.048 μM (cell proliferation)，and an IC50 of 0.048 μM (YAP reporter gene expression)，respsectively.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorYAP
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Research Area——
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Indication——
Chemical Information
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CAS Number2714434-21-4
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Formula Weight529.96
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Molecular FormulaC27H26ClF2N3O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (235.87 mM; Ultrasonic )
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SMILESO=C(NC)C1=CN=C(OCCO)C(F)=C1C=2C(Cl)=C(F)C=C3OC(C=4C=CC=CC4)(CC32)C5NCCC5
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Bordas V, et al. Preparation of biaryl derivatives as YAP/TAZ-TEAD protein-protein interaction inhibitors. World Intellectual Property Organization, WO2021186324 A1. 2021-09-23.
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