Cart
sales@molnova.com
Home - Products - Others - Other Targets - YAP-TEAD-IN-3

YAP-TEAD-IN-3

CAS No. 2714434-21-4

YAP-TEAD-IN-3( —— )

Catalog No. M37083 CAS No. 2714434-21-4

YAP-TEAD-IN-3 is an inhibitor of YAP/TAZ-TEAD interactions with an IC50 of 9 nM for Avi-human TEAD (4217-434).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 744 In Stock
10MG 1007 In Stock
50MG 1376 In Stock
100MG 1841 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    YAP-TEAD-IN-3
  • Note
    Research use only, not for human use.
  • Brief Description
    YAP-TEAD-IN-3 is an inhibitor of YAP/TAZ-TEAD interactions with an IC50 of 9 nM for Avi-human TEAD (4217-434).
  • Description
    YAP-TEAD-IN-3 (compound 155) is a YAP/TAZ-TEAD inhibitor. YAP-TEAD-IN-3 inhibits Avi-humanTEAD4217-434 with an IC50 value of 9 nM. YAP-TEAD-IN-3 also inhibits NCI-H2052 with an GI50of 0.048 μM (cell proliferation)，and an IC50 of 0.048 μM (YAP reporter gene expression)，respsectively.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    YAP
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2714434-21-4
  • Formula Weight
    529.96
  • Molecular Formula
    C27H26ClF2N3O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (235.87 mM; Ultrasonic )
  • SMILES
    O=C(NC)C1=CN=C(OCCO)C(F)=C1C=2C(Cl)=C(F)C=C3OC(C=4C=CC=CC4)(CC32)C5NCCC5
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bordas V, et al. Preparation of biaryl derivatives as YAP/TAZ-TEAD protein-protein interaction inhibitors. World Intellectual Property Organization, WO2021186324 A1. 2021-09-23.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • HBC 530

    HBC 530 is a mimic of green fluorescent protein (GFP) fluorophore for imaging RNA in live cells.

  • EZH2-IN-2

    EZH2-IN-2 is a EZH2 inhibitor extracted from patent WO2018133795A1, Compound Example 69, with an IC50 of 64 nM. EZH2-IN-2 can be used for the research of cancer or precancerous condition related to EZH2 activity.

  • SEC inhibitor KL-1

    SEC inhibitor KL-1 exhibits a dose-dependent inhibitory effect on AFF4-CCNT1 interaction (Ki: 3.48 μM).

Sign In Join Free