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Nav1.8-IN-4

CAS No. 1620846-16-3

Nav1.8-IN-4( —— )

Catalog No. M37057 CAS No. 1620846-16-3

Nav1.8-IN-4 is a potent Nav1.8 channel inhibitor with potential analgesic activity.Nav1.8-IN-4 can be used for pain and neurological related disorders.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
2MG	73	In Stock
5MG	121	In Stock
10MG	188	In Stock
25MG	376	In Stock
50MG	600	In Stock
100MG	918	In Stock
200MG	Get Quote	In Stock
500MG	1841	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Nav1.8-IN-4
Note

Research use only, not for human use.
Brief Description

Nav1.8-IN-4 is a potent Nav1.8 channel inhibitor with potential analgesic activity.Nav1.8-IN-4 can be used for pain and neurological related disorders.
Description

Nav1.8-IN-4 (compound 9a) is a Nav1.8 channel inhibitor (IC50=0.014 μM). Nav1.8-IN-4 can be used for research on pain-related diseases.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Membrane Transporter/Ion Channel
Target

Sodium Channel
Recptor

Sodium Channel
Research Area

——
Indication

——

Chemical Information

CAS Number

1620846-16-3
Formula Weight

406.33
Molecular Formula

C20H14F4N2O3
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 125 mg/mL (307.63 mM; Ultrasonic )
SMILES

O=C1C=C(C=CN1)NC(=O)C2=CC=C(C=C2OC3=CC=C(F)C=C3C)C(F)(F)F
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Corey Anderson, et al. Prodrugs of pyridone amides useful as modulators of sodium channels. Patent WO2015089361A1.

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